Among the environmental factors temperature has a pervasive impact on ectothermic organisms and influences function at all, whole organism to molecular levels of biological organization. In the context of climate changes thermal biology has been at the center of research examining small or large scale physiological patterns in natural populations of marine organisms along latitudinal or intertidal clines. Physiological traits and underlying biochemical mechanisms are very important in setting thermal limits and species boundaries.

Coastal marine systems are among the most ecologically and socio-economically vital on the planet. However, there is a strong scientific consensus that coastal marine ecosystems, along with the goods and services they provide, are threatened by anthropogenic global climate change. Intertidal organisms as mussels inhabit an interface between aquatic and terrestrial habitats where they are exposed to extreme physical conditions during low tides. These organisms experience body temperatures that exceed the temperature of the surrounding air and regularly approach sublethal thermal limits. Organisms residing higher in the intertidal are more likely to experience prolonged thermal and desiccation stresses than are organisms lower in the intertidal. For example mussels found high on the shore will be emersed for longer periods of time and will experience a greater bout of thermal stress. However, the challenge of predicting the outcomes of climate change is made difficult when the combined effects of two or more variables cannot be predicted from the individual effect of each. Non-independent effects are common in nature, and may arise in one of two principle ways: (1) the impact of one factor is either strengthened or weakened by variation in another factor; and (2) the combined influence of two stressors pushes an individual or population beyond a critical threshold that would not be reached via variation in either forcing variable operating in isolation.

Our research is focused on the physiological processes of marine molluscs and fish and how they are influenced either during thermal stress or during ocean acidification. The aim of our works is not only to examine the physiological responses of marine animals to elevation of ambient temperature, but mainly to determine the thermal limits and the physiological performance of marine organisms. It has been indicated by several investigators that the physiological processes contribute markedly in the determination of biogeographical boundaries of marine animals in an ecosystem. Accordingly, by understanding the molecular and metabolic responses of animals during thermal or acidic conditions we can illustrate mechanistically how cells and whole organisms are influenced during thermal stress and, by integrating these results with oceanographic and climatological data, to project the impacts of global warming on their physiological performance. From an ecological part of view these data are very important since we could project changes in the population of species, even more disturbance in the synthesis of communities.

 

Establishment of Klimabionetwork (http://klimabio.web.auth.gr)

The goal of Klimabionetwork is the coordinated activation and organization of research programs for the study of the effects of climatic change on the biology of marine organisms. Specifically the Klimabionetwork designs and perform of experiments to evaluate the impacts of climate chaange on the biology of marine organisms. The long-term objective of this network is to use the collected data for the creation or improvement of current prediction models. In the mean time the network try to record possible changes in the atmospheric composition, focusing on the changes of CO₂ levels, and to collect data concerning larger scale changes in the regional climate of the area. These data will be used in the study of the effect of temperature rise in the biology of organisms, as to ascertain the levels. Forecasts from atmospheric climatic models will be used in the study of the effects of changes of the composition and temperature of the atmosphere to living organisms and ecosystems. The results of these studies are expected to greatly improve our understanding of organism functionality and our ability to manage the ecosystems in which they live. Finally, amongst the objectives of the network is the proliferation of the acquired knowledge and of the new results to students and to concerned citizens. This objective is achieved through hosting talks and oral presentations by distinct scientists and specialists of the area of climatic change and ecophysiology and by attracting mass media

 

 

Funded Projects

a.  Coordinator

1999-2001 (4.000.000 dr.). «Study of acid-base balance of mussels under hypercapnia». Funded by the Greek General Cecreterian of Research and Technology and Institut fur Zoologie, Lehrstute fur Tierphysiologie, Heinrich-Heine-Universitat, Dusseldorf. Coordinator

2004-2005 (17.000 €). «Pilot program on the management and conservation of chavara Modiolus barbatus in Thermaikos Gulf». Funded by Prefecture of Thessalaniki.

2005-2008 (200.000 €). «Management and conservation of chavara Modiolus barbatus in Thermaikos Gulf». Funded by the Greek General Secretariat of Research and Technology (http://chavara.web.auth.gr).

2008-2009. (5.000 €). Establishment of KLIMABIO network (http://klimabio.web.auth.gr). Funding by the Research Committee of Aristotle University. Coordinator

2009-2010 (85.000 €). «Establishment of Biotelemetry Floating and Meteorological Stations in Thermaikos Gulf». Funded by the Research Committee of Aristotle University. Coordinator.

 

b.  Member and scientific collaborator

2010-2012 (505.000€). «Development and application of tools towards an integrated coastal zone management of Thermaikos Gulf: pilot implementation in the west coastal zone» Action 3. Creation of an observatory towards an integrated coastal zone management of Thermaikos gulf and Action 4. Planning and implementation of Environmental Monitoring (http://eyecoast.web.auth.gr). Financed by the EEA/EFTA countries: Iceland, Liechtenstein and Norway within the framework of the EEA Financial Mechanism (“EEA FM”) and by the Hellenic Public Investment Program.  

 

Peer-Reviewed international journal articles

1.   1999: Comparative Biochemistry and Physiology, Part B.

2.   2001: Journal of Experimental Βiology.

3.   2003: Physiological and Biochemical Zoology.

4.   2005: Comparative Biochemistry and Physiology, Journal of Molecular Histology.

5.   2006: Marine Ecology-Progress Series, Marine Biology.

6.   2007: Marine Biology, Aquatic Biology.

7.   2008: Climate Change, Comparative and Biochemistry and Physiology Part Β, Journal of Physiology, Marine Biology, Journal of Comparative Physiology (B), Journal of Thermal Biology.

8.   2009: Marine Biology, Comparative Biochemistry and Physiology, Journal of Experimental Marine Biology and Ecology, Journal of Comparative Physiology (B), Journal of Sellfish Research, ECSS, Journal of Experimental Zoology, Journal of Biological Research, Climate Research.

9.   2010: Physiological and Biochemical Zoology, Comparative and Biochemistry and Physiology Part B, Italian Journal of Zoology, Journal of Molluscan Studies, FEBS Letters, Nueroscience Letters.

10.  2011. Journal of Geophysical Research, Marine Environmental Research, ISRNZoology, Marine Ecology-Progress Series, Physiological and Biochemical Zoology, Journal of Thermal Biology, Biosciences Discussion.

11. 2012. Journal of Experimental Biology, PlosOne, Climate Change

 

 

Evaluator of 6 scientific proposals and projects

1.      ISF (Israel Science Foundation). Adaptation of land snails to desert conditions: from whole animal to molecular mechanisms.

2.     NSF (National Science Foundation Division of Ocean Sciences Biological Oceanography Program). Physiological performance of gelatinous zooplankton in elevated carbon dioxide.

3.      Project evaluation Chilean Science Foundation (FONDECYT). Understanding climate effects of increased temperature and ocean acidification on benthic invertebrates of the southeastern pacific coastal ecosystems.

4.     RESEARCH GRANTS COUNCIL Application for Allocation from the General Research Fund for 2009/2010.Title of Project: Comparative proteomic responses of intertidal limpets to environmental stresses.

5.     RESEARCH GRANTS COUNCIL Application for Allocation from the General Research Fund for 2009 / 2010. Title of Project: Physiological and molecular responses of the Pacific oyster larvae to ocean acidification at warm and low-saline seawater: Immediate and latent effects.

6.     Croatian Science Foundation (CSF), 2011. Title of project: Appearance and spreading of priority hazardous substances in estuaries and coastal sea of republic of Croatia.

 

Member of Editorial board

1.   The Open Oceanography Journal

2.   http://www.bentham.org/open/tooceaj/EBM.htm

3.   Open access, peer-reviewed journal titled "ISRN Zoology,

4.   http://www.hindawi.com/47514196.html

 

Organization of workshops and meetings

24-11-2006: «Climate Change and impacts on marine organisms». The meeting was held under the auspices of the Research Committee of AUTH and in establishing the thematic network KLIMABIO.

18-9-2008: «The mollusks in Thermaikos Gulf-Conservation and Exploitation». The meeting took place at the Congress Center Kiminon of Thessaloniki in collaboration with the local stakeholders. Presented and discussed results from the program “The mollusc in Thermaikos Bay-management and conservation” in the Context of the Operational Programme for Fisheries 2000-2006 Measure 4.6 " Innovative Measures".

21-05-09: Workshop in Congress Center Kiminon of Thessaloniki "Laboratory testing and certifying shellfish health and safety." The meeting was funded by the Prefecture of Thessaloniki.

8-11-2011: International workshop on “Climate change and natural resources management in the Hellenic Coastal Zone”. It is going to be held in Thessaloniki 8-9 November, 2011.

 

Publications

1985

1. Michaelidis B., Lazou A. αnd Beis I. (1985). Purification, catalytic and regulatroty properties of pyruvate kinase from the foot of Patella caerulea (L). Comp. Biochem. Physiol. 82B: 405-412. doi:10.1016/0305-0491(85)90260-3.

 

1987

2. Lazou A., Gaitanaki C., Michaelidis B., Papadopoulos A. αnd Beis I. (1987). Purification, catalytic and regulatory properties of malate dehydrogenase from the foot of Patella caerulea (L). Comp. Biochem. Physiol. 88B: 1033-1040. doi:10.1016/0305-0491(87)90002-2

 

1988

3. Michaelidis B., Gaitanaki C. and Beis I. (1988).  Modification of pyruvate kinase from the foot muscle of Patella caerulea (L.) during anaerobiosis. J. Exp. Zool. 248: 264-271.

http://onlinelibrary.wiley.com/doi/10.1002/jez.1402480304/pdf

 

1989

4. Lazou A., Michaelidis B. and Beis I. (1989). Evidence for glycolytic enzyme binding during anaerobiosis of the foot muscle of Patella caerulea (L.). J. Comp. Physiol. 158B: 771-777. http://www.springerlink.com/content/rr63457052t872t8/fulltext.pdf

5. Michaelidis B., Lazou A. and Beis I. (1989). The possible role of enzyme binding in the control of glycolysis in the foot muscle of Patella caerulea (L.) during electrical stimulation. Comp. Biochem. Physiol. 93B: 247-250.

doi:10.1016/0305-0491(89)90076-X

 

1990

6. Michaelidis B. and Beis I. (1990). Studies on the anaerobic energy metabolism in the foot muscle of marine gastropod Patella caerulea (L.). Comp. Biochem. Physiol. 95B: 493-500. doi:10.1016/0305-0491(90)90009-I

7. Papadopoulos A., Michaelidis B. and Lazou A. (1990). Tissue specific isoenzyme of D-Lactate dehydrogenase from the foot, mantle and hepatopancreas of Patella caerulea (L.). Purification and propeerties. Int. J. Biochem. 22:601-605.

doi:10.1016/0020-711X(90)90035-2

8. Michaelidis B. and Storey B.K. (1990). Phosphofructokinase from the anterior byssus retractor muscle of Mytilus edulis: Modification of the enzyme in anoxia and by endogenous protein kinases. Int. J. Biochem. 22: 759-765.

doi:10.1016/0020-711X(90)90012-R

9. Michaelidis B., Papadopoulos A. and Beis I. (1990). Effect of anoxia on the kinetic properties of pyruvate kinase and phosphofructokinase, and on glycogen phosphorylase activity in marine worms and earth worms. J. Comp. Physiol. 160B: 201-206.

http://www.springerlink.com/content/jk2673t1458401m9/fulltext.pdf

10. Michaelidis B. and Storey B.K. (1990). Influence of pH on the regulatory properties of anaerobic and anoxic forms of pyruvate kinase in a marine whelk. J. Exp. Zool. 253: 245-251. http://onlinelibrary.wiley.com/doi/10.1002/jez.1402530303/pdf

11. Michaelidis B. and Storey B.K. (1990). Anaerobiosis and the regulation of glycolytic enzymes in the sea anemone Metridium senile. J. Exp. Zool. 256: 145-161. http://onlinelibrary.wiley.com/doi/10.1002/jez.1402560205/pdf

12. Michaelidis B. and Storey B.K. (1990). Interactions of temperature and pH on the regulatory properties of pyruvate kinase from organs of marine mollusc. J. Exp. Mar. Biol. Ecol. 140: 187-196. doi:10.1016/0022-0981(90)90126-W

 

1991

13. Michaelidis B. and Storey B.K. (1991). Evidence for phosphorylation-dephosphorylation control of phosphofructokinase from the anoxia-tolerant sea mussel Mytilus edulis. J. Exp. Zool. 257: 1-9.

http://onlinelibrary.wiley.com/doi/10.1002/jez.1402570102/pdf

14. Papadopoulos A., Michaelidis B. and Beis I. (1991). Pyruvate kinase from the earth worm Allobophora calliginosa: Modification of the enzyme during anaerobiosis. Can. J. Zool. 69: 251-254.

http://rparticle.web-p.cisti.nrc.ca/rparticle/AbstractTemplateServlet?journal=cjz&volume=69&year=1991&issue=69&msno=z91-038&calyLang=eng

 

1993

15. Kaloyianni M., Michaelidis B. and Moutou K. (1993). Effect adenosine on glucose metabolism of Rana ridibunda erythrocytes.  J. Exp. Biol. 177: 41-50.

16. Michaelidis B., Rofalikou E. and Beis I. (1993). The effect of serotonin (5-hydroxyptamine) on glycolysis in the perfused ventricle of the fresh-water bivalve Anodonta cygnea: Evidence for phosphorylation/dephosphorylation control of phosphofructokinase. J. Exp. Biol. 180: 15-25.

 

1994

17. Michaelidis B. and Pardalidis T. (1994). Regulation of pyruvate kinase (PK) from the ventricle of land snail Helix lucorum during early and prolonged estivation and hibernation. Comp. Βiochem. Physiol. 107B: 585-591. doi:10.1016/0305-0491(94)90189-9 

18. Michaelidis B. and Athanasiadou P. (1994). Effect of reduced oxygen tension on the heart rate and the kinetic properties of glycolytic key enzymes PFK, PK and glycogen phosphorylase from the freshwater mussel Anodonta cygnea (L.). Comp. Biochem. Physiol. 108 B: 165-172. doi:10.1016/0305-0491(94)90062-0

 

1997

19. Pappa-Louisi A., Rofalikou E. and Michaelidis B. (1997).  Determination of biogenic amines and related compounds in the ganglia and the auricle and ventricle of the heart of the snail  Helix lucorum (L.) by  HPLC with amperometric detection. J. Liq. Chrom. & Rel. Techol., 20(15), 2427-2439. http://dx.doi.org/10.1080/10826079708002713

20. Michaelidis B. and Vasiliou E. (1997). Evidence for the short-term regulation of glycolytic flux in the isolated perfused ventricle of the land snail Helix lucorum (L.) after treatment with serotonin (5-hydroxytryptamine). J. Comp. Physiol.  167 B: 508-516.

http://www.springerlink.com/content/pujmj742rh0tcfg3/fulltext.pdf

 

1999

21. Rofalikou E., Pappa-Louisi A. and Michaelidis B. (1999).  Effects of estivation on the levels of biogenic amines and related compounds in the ganglia, the auricle and the ventricle of the heart of the pulmonate land snail Helix lucorum (L): evidence for physiological roles of serotonin and dopamine in the control of heart function during estivation. J. Exp. Zool. 283: 137-146.

http://onlinelibrary.wiley.com/doi/10.1002/(SICI)1097-010X(19990201)283:2%3C137::AID-JEZ4%3E3.0.CO;2-H/pdf

22. Michaelidis B., Pallidou A. and Vakouftsi P. (1999).  Effect of anoxia on the extra- and intracellular acid-base status in the land snail Helix lucorum (L): lack of evidence for a relationship between pyruvate kinase down-regulation and acid-base status. J. Exp. Biol. 202: 1667-1675. http://jeb.biologists.org/cgi/reprint/202/12/1667

23. Michaelidis B., Rofalikou E. and  Grieshaber K. M (1999). Effect of hypercapnia on force and rate of  contraction and intracellular pH of perfused ventricles from the land snail Helix lucorum (L.). J. Exp. Biol. 202: 2993-3001.

http://jeb.biologists.org/cgi/reprint/202/21/2993

 

2001

24. Staikou A., Stiakakis M. and Michaelidis B. (2001). Effects of prolonged acclimation to cold on the extra-and intracellular acid-base status in the land snail Helix lucorum (L.). Physiol. Biochem. Zool. 74 (3): 404-412.

http://www.journals.uchicago.edu/doi/abs/10.1086/320422

 

2002

25. Michaelidis B. (2002). Studies on the extra- and intracellular acid-base status and its role on metabolic depression in the land snail Helix lucorum (L.) during estivation. J. Comp. Physiol. 72 B: 347-354.

http://www.springerlink.com/content/5ah3bgvqc23q9064/fulltext.pdf

26. Michaelidis B., Loumbourdis N. and Kapaki E. (2002). Analysis of monoamines, adenosine and GABA in tissues of the land snail Helix lucorum and lizard Agama stellio stellio during hibernation. J. Exp. Biol. 205: 1135-1144.

http://jeb.biologists.org/cgi/reprint/205/8/1135

 

2005

27. Michaelidis B., Haas  D. and Grieshaber K. M. (2005). Extracellular and intracellular acid-base status with regard to energy metabolism in the oyster Crassostrea gigas during exposure to air. Physiological and Biochemical Zoology 78 (3): 373-383.

http://www.journals.uchicago.edu/doi/abs/10.1086/430223

28. Michaelidis B., Ouzounis C, Paleras A. and Pörtner H.O. (2005). Effects of long-term moderate hypercapnia on the growth rate and acid-base balance in the marine bivalve Mytilus galloprovincialis. Mar. Ecol.-Prog. Ser. 293: 109-118.

http://www.int-res.com/articles/meps2005/293/m293p109.pdf

29. Pörtner Η.Ο., Langenbuch Μ. and Michaelidis B. (2005). Synergetic effects of increased CO₂, temperature and hypoxia on marine animals. J. Geophys. Res.-Oceans 110 (C9): art. no. C09S10 SEP 23.

http://www.agu.org/pubs/crossref/2005/2004JC002561.shtml

 

2007

30. Michaelidis B., Vavoulidou D., Rousou X. and Pörtner Η.Ο. (2007). The potential role of CO₂ in initiation and maintenance of estivation in the land snail Helix lucorum. Physiological and Biochemical Zoology 80 (1): 113-124.

http://www.journals.uchicago.edu/doi/abs/10.1086/509210

31. Michaelidis B., Spring A. and Pörtner Η.Ο. (2007). Effects of long-term acclimation at hypercapnia on acid-base status and metabolism in tissues of Sparus aurata. Mar. Biol. 150 (6): 1417-1429.

http://www.springerlink.com/content/p4765g527k775211/fulltext.pdf

32. Anestis A., Lazou A., Pörtner H.O. and Michaelidis B. (2007). Behavioural, metabolic and molecular stress indicators in the marine bivalve Mytilus galloprovincialis during long-term acclimation at increasing ambient temperature. Am. J. Physiol.-Regul. Integr. Comp. Physiol. 293: R911–R921.

http://ajpregu.physiology.org/cgi/content/full/293/2/R911#BIBL

 

2008

33. Anestis A., Pörtner H.O. and Michaelidis B. (2008). Metabolic and molecular stress indicators in the marine bivalve Mytilus barbatus during long-term acclimation at increasing ambient temperature. J. Exp. Biol. 211:2889-2898. http://jeb.biologists.org/cgi/reprint/211/17/2889

34. Michaelidis B., Kiriakopoulou-Sklavounou P. Staikou A., Papathanasiou I. and Konstantinou K. (2008). Glycolytic adjustments in tissues of frog Rana ridibunda and land snail Helix lucorum during seasonal hibernation. Comp. Biochem. Physiol. Part A 151: 582–589. doi:10.1016/j.cbpa.2008.07.017  

 

2009

35. Feidantis K., Pörtner H.O., Lazou A., Kostoglou B. and Michaelidis B. (2009). Metabolic and molecular stress responses of marine fish Sparus aurata during exposure to increasing sea water temperature. Mar. Biol. 156: 797–809.

http://www.springerlink.com/content/hw2t273xj3268k96/fulltext.pdf 

36. Michaelidis B., Hatzikamari M., Antoniou V., Anestis A. and Lazou A. (2009). Stress activated protein kinases, JNKs and p38 MAPK, are differentially activated in ganglia and heart of land snail Helix lucorum (L.) during seasonal hibernation and arousal. Comp. Biochem. Physiol. Part A, 153: 149-153.  doi:10.1016/j.cbpa.2009.01.021

38. Ioannou S., Anestis A., Pörtner H.O. and Michaelidi B. (2009). Seasonal patterns of metabolism and the heat shock response (HSR) in farmed mussels Mytilus galloprovincialis: perspectives for global warming. J. Exp. Mar. Biol. Ecol. 381: 136-144.

37. Michaelidis B., Kyriakopoulou-Sklavounou P., Triantafyllidis A. and Michaelidis S. (2009). Isoforms of enzymes of intermediated metabolism during the hibernation of the water frog Rana ridibunda. Journal of Biological Research 14: 191-198. doi:10.1016/j.jembe.2009.09.014  

 

2010

39. Anestis A., Pörtner H.O., Karagiannis D., Angelidis P., Staikou A. and Michaelidis B. (2010). Response of Mytilus galloprovincialis (L.) to increasing sea water temperature and to marteliosis: Metabolic and Physiological parameters. Comp. Biochem. Physiol., Part A 156: 57-66. doi:10.1016/j.cbpa.2009.12.018 

40. Kyprianou T-D., Pörtner H.O., Anestis A., Kostoglou B., Feidantsis K. and Michaelidis B. (2010). Metabolic and molecular stress responses of gilthead seam bream Sparus aurata during exposure to low ambient temperature: an analysis of mechanisms underlying the winter syndrome. J. Comp. Physiol. B 180:1005–1018. http://www.springerlink.com/content/t674270w16t52201/fulltext.pdf

41. Anestis A., Pörtner H.O. and Michaelidis B. (2010). Anaerobic metabolic patterns related to stress responses in hypoxia exposed mussels Mytilus galloprovincialis. J. Exp. Mar. Biol. Ecol. 394: 123–133. doi:10.1016/j.jembe.2010.08.008 

 

2011

42. Katsikatsou M., Anestis A._, Pörtner H.O., Kampouris T. and Michaelidis B. (2011). Field studies on the relation between the accumulation of heavy metals and metabolic and HSR in the bearded horse mussel Modiolus barbatus. Comp. Biochem. Physiol, Part C 153: 133–140. http://www.sciencedirect.com/science/article/pii/S1532045610001729

 

2012

43. Dimitriadis V.K., Gougoula C., Anestis A., Pörtner H.O. and Michaelidis B. (2012). Monitoring the biochemical and cellular responses of marine bivalves during thermal stress by using biomarkers. Marine Environmental Research 73: 70-77.

44. Feidantsis K., Pörtner H.O., Markou T., Lazou A. and Michaelidis B. (2012). Involvement of p38 MAPK in the induction of Hsp70 during acute thermal stress in red blood cells of the gilthead sea bream, Sparus aurata. J. Exp. Zool A 317: 303-310.

45. Katsikatsou M., Anestis A., Vratsistas A., Pörtner O.H. and Michaelidis B. (2012). Field studies identify molecular and metabolic responses of Mediterranean bivalve Modiolus barbatus to climate warming. MEPS 449: 183-196.

46. Anestis A., Feidantsis K., Vasara E., Kyriakopoulou-Sklavounou P. and Michaelidis B. (2012). Seasonal variations of cellular stress response in the heart and gastrocnemius muscle of the water frog (Pelophylax ridibundus). Comp. Biochem. Physiol. A 162: 331-339. 

47. Feidantsis K., Antonopoulou E., Lazou A., Pörtner H.O., Michaelidis B. (2012). Seasonal variations of cellular stress response of the gilthead sea bream (Sparus aurata). J. Comp. Physiol. B. doi:10.1007/s00360-012-0735-y.

 

Other publications

48. Pörtner H.O., Bickmeyer U., Bleich M., Bock C., Brownlee C., Melzner F., Michaelidis B.,  Sartoris J. F. and Storch D. (2010). Studies of acid-base status and regulation. In: “Guide to best practices in ocean acidification research and data reporting”, (Edited by U. Riebesell, V. Fabry, L. Hansson and J.-P. Gattuso), pp 137-166. Luxemburg Publications Office of the European Union. DOI: 10.2777/58454, ISBN: 978-92-79-11118-1

http://epoca-project.eu/index.php/guide-to-best-practices-for-ocean-acidification-research-and-data-reporting.html.

49. Michaelidis B., Pörtner H.O., Tomanek L. and Sokolova I. (2013). «Advances in predicting the impacts of global warming on the mussels Mytilus galloprovincialis in the Mediterranean Sea». In: The Mediterranean Sea: Its History and Present Challenges. (Editors: Stefano Goffredo and Zvy Dubinsky) (In Press).

 

Under revision

1. Feidantsis κ., Kaitetzidou Ε., Mavrogiannis Ν., Michaelidis Β., Kotzamanis Υ. and Antonopoulou Ε. (2013). Effect of taurine enriched diets on the Hsp expression, MAPK activation and the antioxidant defence of the European Sea Bass (Dicentrarchus labrax).

2. Feidantsis K., Pörtner H.O. and Michaelidis B. (2013). Metabolic and molecular stress responses of the gilthead seabream Sparus aurata to synergistic effects of low pH and temperature.

3. Feidantsis K., Anestis A. and Michaelidis B. (2013). Seasonal variations of anti-/apoptotic and antioxidant proteins in the heart and gastrocnemius muscle of the water frog Pelophylax ridibundus.  

4. Evaggelopoulou N.E., Samanidou V.F., Michaelidis B. and Ioannis Papadoyannis (2013). Multi-residue high performance liquid chromatography-diode array detection determination of seven quinolones in fish feed and farmed gilthead seabream (Sparus aurata L.) after medicated feed administration of oxolinic acid and flumequine.

5. Feidantsis K., Hans O. Pörtner O.H. and Michaelidis B. (2013). Seasonal variations of metabolism in the gilthead sea bream (Sparus aurata). Correlations to the threshold induction temperature.

 

Publications in International Conferences Proceedings – Presentations 

1. Michaelidis B. (1998). “Physiological effects of hypercapnia on cellular functions in a land snail and in a marine bivalve”. Workshop on the topic Environmental Impacts of CO₂ storage in the Oceans. Bergen, Norway.

2. Paleras A., Grieshaber M. and Michaelidis B. (2002). “Greenhouse effects and growth rate of marine bivalve Mytilus galloprovicialis”. 9th International Congress on the Zoogeography and Ecology of Greece and Adjacent regions, p. 117. Thessaloniki.

3. Ouzounis C., Grieshaber M. and Michaelidis B. (2002). “Greenhouse effects and the acid-base balance of marine bivalve Mytilus galloprovincialis”. 9th International Congress on the Zoogeography and Ecology of Greece and Adjacent regions. P.115. Thessaloniki.

4. Pörtner H.O., Langenbuch M. and Michailidis B. (2004). Effects of CO₂ on marine animals: Time scales, processes, and limits of adaptation. ΙCCP Symposium: Oceans in a high CO₂ world. Paris 2004.

5. Anestis A., Lazou A. and Michaelidis B. (2006). “The role of heat shock proteins (hsps) in the vertical distribution of marine bivalves in the thermaikos gulf. a biochemical tool for the conservation of marine bivalves during thermal stress”. 10^ο International Congress on the Zoogeography and Ecology of Greece and Adjacent regions. Patra.

6. Karagiannis D., Angelidis P., Staikou A., Michaelidis B. (2006). “The effect of Marteilia sp. infestation on the scope for growth of mussels Mytilus galloprovinciallis L.” (Presented to the annual conference of the World Aquaculture Society (WAS), WORLD AQUACULTURE 2006 on May 9-13, in Firenze (Florence), Italy.

7. Feidantsis K., Lazou A. and Michaelidis B. (2007). “Tissue specific response of Hsps and MAPKs in marine fish Sparus aurata exposed to increased temperature”. Hellenic Society of Biochemistry and Molecular Biology. Book of Abstracts of the 59th Meeting, pp 94.

8. Feidantsis K., Pörtner H.O., Lazou A., Kostoglou B., Michaelidis B. (2008). “Metabolic and molecular stress responses of the gilthead seabream Sparus aurata during long term exposure to increasing temperatures”. Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology, Volume 151, Issue 1, Supplement 1, September 2008, Page S26.

9. K. Feidantsis, O. H. Portner, A. Lazou, E. Antonopoulou and B. Michaelidis (2009). “Seasonal variations in metabolism and cellular stress response in the white muscle of the giltehead sea bream (Sparus aurata)”. Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology, Volume 154, Issue 1, Supplement 1, Page S3

10. M. Katsikatsou, O.H.Pörtner and B. Michaelidis (2009). Field study of the molecular and metabolic responses of the bivalve Modiolus barbatus. Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology Volume 154, Issue 1, Supplement 1, Page S8

11. A. Anestis, O.H. Pörtner and B. Michaelidis (2009). “Evidence for close relationship between anaerobic metabolism and Heat Shock Response (HSR) in the marine bivalve Mytilus galloprovincialis”. Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology Volume 154, Issue 1, Supplement 1, Page S8

12. G.K. Tachtatzis, A. Staikou and B. Michaelidis (2009). “Seasonal metabolic and activity pattern in the land snail Faustina trizona olympica”. Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology Volume 154, Issue 1, Supplement 1, Page S34.

13. Katsikatsou M., Anestis A., Pörtner H.O. and Michaelidis B. (2010). “Integrated effects of molecular and metabolic stress in Modiolus barbatus in the field”. 27th Congress of the European Society of Comparative Biochemistry and Physiology, Alessandria, Italy, September 5-9, 2010 Date: SEP 05-09, 2010 Alessandria, ITALY- Biological effects of climatic changes and pollution: from biomarkers to system biology. Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology, Volume 157, Issue 1,   Pages S50-S50.  

14. Feidantsis K., Markou T., Pörtner H.O., Lazou A. and Michaelidis B. (2010). “Seasonal variations of p38 MAPK phosphotylation and heat shock protein expression in red blood cells of Sparus aurata. Involvement of p38 MAPK in the induction of hsp70”. 27th Congress of the European Society of Comparative Biochemistry and Physiology, Alessandria, Italy, September 5-9, 2010 Date: SEP 05-09, 2010 Alessandria, ITALY- Biological effects of climatic changes and pollution: from biomarkers to system biology. Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology, Volume 157,   Issue 1, Pages S49-S50. 

15. Michaelidis B., Anestis A. and Feidantsis K. (2011). Impacts of Climate Change on aquaucltures of mussels. 4^ο International Conference of Aquaculture-Fisheries. Volos, Greece.

  

Publications in Hellenic Conference Proceedings

1. Μιχαηλίδης Β. και Μπέης Ι. (1982). «Μελέτη του μεταβολισμού ενέργειας στο μυ της Patella caerulea». Πρακτικά 4^ου Επιστημονικού Συνεδρίου Ελληνικής Εταιρείας Βιολογικών Επιστημών, Σελ. 68-71. ΘΕΣΣΑΛΟΝΙΚΗ.

2. Μιχαηλίδης Β. και Μπέης Ι. (1983). «Μελέτη των ιδιοτήτων της κινάσης του πυροσταφυλικού οξέος από εκχύλισμα μυός της Patella caerulea». Πρακτικά 5^ου Επιστημονικού Συνεδρίου της Ελληνικής Εταιρείας Βιολογικών Επιστημών, σελ. 67-68. ΠΑΤΡΑ.

3. Μιχαηλίδης Β. και Μπέης Ι. (1984α). «Καθαρισμός της κινάσης του πυροσταφυλικού οξέος από το μυ του ποδιού της Patella caerula και μελέτη των ιδιοτήτων της». Πρακτικά 6^ου Επιστημονικού Συνεδρίου της Ελληνικής Εταιρείας Βιολογικών Επιστημών, τεύχος α, σελ. 105-106. ΑΘΗΝΑ.

4. Μιχαηλίδης Β. και Μπέης Ι. (1984β). «Αναερόβιος μεταβολισμός ενέργειας στο μυ του ποδιού του θαλάσσιου μαλακίου Patella caerulea». Πρακτικά 6^ου Επιστημονικού Συνεδρίου της Ελληνικής Εταιρείας Βιολογικών Επιστημών, τεύχος Α, σελ. 113-114. ΑΘΗΝΑ.

5. Μιχαηλίδης Β., Γαϊτανάκη Κ. και Μπέης Ι. (1986). «Τροποποίηση της κινάσης του πυροσταφυλικού οξέος από το μυ του ποδιού της Patella caerulea  κατά τη διάρκεια της αναεροβίωσης». Πρακτικά 8^ου Επιστημονικού Συνεδρίου της Ελληνικής Εταιρείας Βιολογικών Επιστημών, σελ. 23-24. ΙΩΑΝΝΙΝΑ.

6. Παπαδόπουλος Α., Μιχαηλίδης Β. και Λάζου Α. (1989). «Μελέτη των κινητικών χαρακτηριστικών της αφυδρογονάσης του γαλακτικού οξέος από το μυ του ποδιού, του μανδύα και το ηπατοπάγκρεας του θαλάσσιου μαλακίου Patella caerulea». Πρακτικά 11^ου Επιστημονικού Συνεδρίου της Ελληνικής Εταιρείας Βιολογικών Επιστημών, σελ. 145-146. ΚΟΜΟΤΗΝΗ.

7. Μιχαηλίδης Β. και Καλογιάννη Μ. (1992). «Επίδραση της αδενοσίνης στο μεταβολισμό της γλυκόζης των ερυθροκυττάρων του Rana ridibunda». Πρακτικά 13^ου Επιστημονικού Συνεδρίου της Ελληνικής Εταιρείας Βιολογικών Επιστημών.

8. Αποστολόπουλος Κ. και Μιχαηλίδης Β. (1993). «Επίδραση της σεροτονίνης στον καρδιακό ρυθμό και στο ποσοστό σύνδεσης των γλυκολυτικών ενζύμων στα υποκυτταρικά στοιχεία στην καρδιά του χερσαίου σαλιγκαριού Helix lucorum». Πρακτικά 15^ου Επιστημονικού Συνεδρίου της Ελληνικής Εταιρείας Βιολογικών Επιστημών, σελ. 320-322. ΦΛΩΡΙΝΑ-ΚΑΣΤΟΡΙΑ.

http://www.eebe.gr/userfiles/file/praktika/1993_Praktika_Florina_Kastoria.pdf

9. Ρωφαλίκου Ε., Παππά Α-Λ. και Μιχαηλίδης Β. (1995). «Επίδραση της ανοξίας, της θερινής και της χειμερινής νάρκης στα επίπεδα της σεροτονίνης και ντοπαμίνης στην καρδιά του χερσαίου σαλιγκαριού Helix lucorum (L.)». Πρακτικά 17^ου Επιστημονικού Συνεδρίου της Ελληνικής Εταιρείας Βιολογικών Επιστημών, σελ. 461-463. ΠΑΤΡΑ.

10. Ntailianis S., Michaelidis B. (2000). Determination of biogenic amines and adenosine in ganglia and heart of the land snail Helix lucorum during long - term anoxia. Proceedings 22th Panhellenic Meeting of HSBS, p. 191, Skiathos Isl.

11. Portokalidou X. and Michaelidis B. (2000). Determination of biogenic amines and adenosine in ganglia and heart of the land snail Helix lucorum (L.) under conditions of low temperature and hibernation. Proceedings 22th Panhellenic Meeting of HSBS, p. 225, Skiathos Isl.

12. Vavoulidou D., Anestis A. and Michaelidis Β. (2004). Greenhouse phenomenon and its effect in the acid – base balance of land snail Helix lucorum (L.). Hellenic Society for Biological Sciences, Proceedings of 26th Scientific Conference, p. 31, Volos.

13. Anestis A. and Michaelidis B. (2004). Effects of sea water temperature on the enzymatic activity of pk in the marine bivalve Mytilus galloprivincialis. Hellenic Society for Biological Sciences, Proceedings of 26th Scientific Conference, p. 13, Volos.

14. Anestis A., Lazou A., and Michaelidis B. (2005). Expression of hsp70 and hsp90 and activation of μαρkinases (p38 and JNKs) in tissues of Mytilus galloprovincialis after long term acclimation at different temperatures. Hellenic Society for Biological Sciences, Proceedings of 27th Scientific Conference, p. 14, Nafplio.

15. Spring A., and Michaelidis B. (2005). Effect of hypercapnia on the aerobic capacity of the sea fish Sparus aurata. Hellenic Society for Biological Sciences, Proceedings of 27th Scientific Conference, p. 376, Nafplio.

16. Kostoglou B., C. Muswamba Νday and Michaelidis B. (2005). Metabolic responses of sea fish Sparus aurata during long-term acclimation at different temperatures. Hellenic Society for Biological Sciences, Proceedings of 27th Scientific Conference, p. 196, Nafplio.

17. Roussou X., Paterakis E. and Michaelidis B. (2005). Effect of hypercapnia on the aerobic capacity of land snails Helix lucorum and Helix aspersa. the role of dlactate dehydrogenase on the distribution of land snails. Hellenic Society for Biological Sciences, Proceedings of 27th Scientific Conference, p. 348, Nafplio.

18. Anestis A., Lazou A. and Michaelidis B. (2006). Determination of the upper thermal limits in the marine bivalve Μytilus galloprovincialis. Βiochemical and metabolic responses. Hellenic Society for Biological Sciences, Proceeding of 28^th Scientific Conference, p 10, Ioannina.

19. Anestis A., Lazou A., and Michaelidis B. (2006). Biochemical responses in the sublittoral bivalve Modiolus barbatus. Determination of the upper thermal limits. Hellenic Society for Biological Sciences, Proceeding of 28^th Scientific Conference, p 12,  Ioannina.

20.Papathanasiou I., Kyriakopoulou-Sklavounou P., Michaelidis B. Biochemical responses of the frog Rana ridibunda during hibernation. Hellenic Society for Biological Sciences, Proceeding of 28^th Scientific Conference, p 316, Ioannina.

21. Anestis A., Pörtner H. O., Staikou A., and Michaelidis B. Effects of temperature on the energetics and glycolytic enzymes activities in the marine bivalve Mytilus galloprovincialis (L.). Proceedings of the 29th Scientific Conference of Hellenic Association for Biological Sciences, p. 19, Kavala

22. Kydonopoulou K., Michaelidis B., and Staikou A. (2007). The effects of hypercapnia on growth and aerobic capacity in the land snail Helix aspersa. Proceedings of the 29th Scientific Conference of Hellenic Association for Biological Sciences, p. 203, Kavala.

23. Michaelidis B. (2007).Biochemical and metabolic responses of mussels and fish to a warmer marine environment. Proceedings of the 29th Scientific Conference of Hellenic Association for Biological Sciences, p. 267, Kavala

24. Κ. Κουκάρας, Ν. Καλογεράκης, Β. Μιχαηλίδης, Σ. Σαμαρτζή, Α. Τσαγκούρου, Γ. Μεθενίτου (2007). “Innovating system of heavy metal removal from the mussels”. 1^ο Hellenic Confeence of Ventiriany and Health, Athens 2007.

25. Φειδάντσης Κ., Λάζου Α. και Μιχαηλίδης Β. (2007). Determination of thermal threshold temperature inducinf induction of Hsps in the tissues of Sparus aurata. Proceedings of the 29th Scientific Conference of Hellenic Association for Biological Sciences, p. 268, Kavala.

26. Michaelidis S., Kyriakopoulou-Sklavounou P., Triantafyllidis A., Michaelidis B. (2008). Isoforms of glycolytic enzymes during the hibernation of the waterfrog Rana ridibunda. Proceedings of the 30th Scientific Conference of Hellenic Association for Biological Sciences, p 317, Thessaloniki.

27. Anestis Α., Pörtner Η.Ο. and Michaelidis Β. (2009). Evidence for close relationship between anaerobic metabolism pattern of mytilus galloprovincialis and heat shock response (HSR). Proceedings of the 31st Scientific Conference of Hellenic Association for Biological Sciences, p 17, Patra.

28. Tachtatzis G.K., Staikou A., and Michaelidis B. (2009). Seasonal pattern of metabolism in the endemic land snail Faustina trizona olympica. Proceedings of the 31st Scientific Conference of Hellenic Association for Biological Sciences, p. 343, Patra.

D.29. Feidantsis K., Antonopoulou E. and Michaelidis B. (2009). Seasonal changes in the aerobic capacity of Sparus aurata. «9ο Πανελλήνιο Συνέδριο Ωκεανογραφίας και Αλιείας», Πάτρα, 13-16 Μαΐου, 2009, σελ. 722-726.

30. Feidantsis K., Pörtner H.O., Michaelidis B. (2010). Cellular variations in metabolism and cellular stress response in the red muscle of the gilthead sea bream (Sparus aurata). 14ο Πανελλήνιο Συνέδριο Ιχθυολόγων, Αλιεία - Υδατοκαλλιέργειες, μια πολυδιάστατη προσέγγιση, σελ. 233-236.

31. Katsikatsou M., Vratsistas A., Anestis A., Ntokou A., Pörtner H.O. and Michaelidis B. (2010). Field study of the seasonal stress responses of the bivalve Modiolus barbatus. 32nd Scientific Conference of the Hellenic Society for Biological Sciences Karpenissi, p. 139.

32. Μιχαηλίδης Β., Ανέστης Α., Φειδάντσης Κ. (2011). Πιθανές επιπτώσεις της κλιματικής αλλαγής στις υδατοκαλλιέργειες των δίθυρων. 4ο Διεθνές Συνέδριο Υδροβιολογίας–Αλιείας. Βόλος 9-11.

33. Ntokou A., Andreas A., Michaelidis B. (2011). Synergetic effects of temperature and hypercapnia on the metabolism of the bivalve Mytilus galloprovincialis. Proccedings of the 33rd Scientific Conference of Hellenic Society for Biological Sciences, EDESSA, pp. 229.